Is the Dog a Possible Reservoir for Cutaneous Leishmaniasis in Suriname?
نویسندگان
چکیده
Cutaneous leishmaniasis (CL) is an emerging disease in Suriname, with at least 200 cases per year. Little is known about the biology of CL in the country. The most important parasite species is Leishmania Viannia guyanensis, but possible vectors and reservoirs are hardly incriminated. In the present study, it was investigated whether the dog could possibly be a zoonotic reservoir for the disease in Suriname. Forty-seven dogs were examined for overt clinical signs of leishmaniasis, and blood samples were collected on filter paper for serology (direct agglutination test) and molecular biology (by polymerase chain reaction). Three dogs had clinical signs that could be compatible with canine cutaneous leishmaniosis: dermatitis (two) or nasal lesion (one). Two dogs were seropositive with DAT (titre > 1 : 1600), and three animals had a borderline titre (1 : 800). All other animals (n = 42) were DAT negative. PCR analysis found Leishmania DNA equivalent to 1 parasite per mL in only one dog at a first round of analysis, but this animal was negative after retesting. The clinical, serological, and molecular data show some preliminary lines of evidence that canine leishmaniosis is present in Suriname, but further studies are needed to incriminate the reservoir, including a possible sylvatic cycle.
منابع مشابه
Clinical, biological, and anthropological aspects of leishmaniasis in Suriname - report of the final meeting of the Integrated Program
The parasitic disease cutaneous leishmaniasis is an increasing health problem in many countries including the Republic of Suriname. Diagnosis is difficult and treatment options are few, while the sideeffects are serious and treatment failure is not uncommon. Insight into the epidemiology and biology of the disease in Suriname is scant. Cutaneous leishmaniasis also puts a significant economic bu...
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ورودعنوان ژورنال:
دوره 2013 شماره
صفحات -
تاریخ انتشار 2013